Production process and application of Tetrakis hydroxymethyl phosphonium sulfate(THPS)

Tetrakis hydroxymethyl phosphonium sulfate（THPS)，CAS：55566-30-8 is an important organophosphorus compound with efficient sterilization, flame retardant and other characteristics.The following is a detailed description of its production process and application.

1.Production process of tetrakis hydroxymethyl phosphate sulfate

The production process of THPS mainly includes the following steps:

1.1. Raw material preparation

-Phosphate (PH3): as a source of phosphorus, usually by white phosphorus or phosphate reduction.

-Formaldehyde (HCHO): Provide the hydroxymethyl group (-CH2OH) as a hydroxymethylation reagent.

-Sulfuric acid (H2SO4): provide sulfate (SO4²).

1.2. Reaction process

The THPS production is mainly done by a two-step reaction:

(1) Hydroxymethylation reaction

Phosphine reacts with formaldehyde under alkaline conditions to produce a tetrahydroxymethyl phosphine, which is usually performed under mild conditions and controls temperature and pH.

(2) Sulfuration reaction

The reaction of tetrahydroxymethyl phosphate salt with sulfuric acid to form Tetrakis hydroxymethyl phosphonium sulfate（THPS)，CAS：55566-30-8, the reaction should be carried out under acidic conditions, and the amount of sulfuric acid should be strictly controlled.

1.3. Purification

-Crystallization: THPS is from the reaction solution by cooling or evaporation the solvent.

-Filter: to separate the crystal from the mother liquor.

-Washing: Wash the crystals with deionized water or organic solvent to remove impurities.

-Dry: Dry the crystals at low temperature to give a high-purity THPS product.

1.4. Packaging and storage

-THPS is usually stored and transported in aqueous solution at a concentration of about 75%.

-Packaging materials shall be corrosion resistant, such as polyethylene or polypropylene containers.

2. Application of Tetrakis hydroxymethyl phosphonium sulfate（THPS)，CAS：55566-30-8

THPS has important applications in several fields due to its unique chemical properties:

2.1. Bactericide

-Industrial water treatment: THPS is a broad-spectrum fungicide, which has efficient killing of bacteria, fungi and algae. It is widely used in industrial water treatment fields, such as cooling towers, oil field water injection system, paper mills and so on.

-Oilfield applications: THPS can effectively control sulfate reducing bacteria to prevent pipeline corrosion and blockage.

-Environmental advantages:THPS is easy to degrade in the environment,low toxicity,it is a relatively environmentally friendly fungicide.

2.2. Flame retardant

-Textile: THPS can be used for the flame retardant treatment of cotton, polyester and other fabrics, giving the material excellent flame retardant performance.

-Plastics and polymers: as a reactive flame retardant, THPS can co-polymer with other monomers to improve the flame retardant of the material.

2.3. Chemical intermediates

-THPS can be used as an intermediate for the synthesis of other phosphorus-containing compounds, such as for the preparation of season salt, phosphorus-series flame retardant, etc.

2.4. Other applications

-Agriculture: as a fungicide or plant growth regulator.

-Medicine: used for the synthesis of certain phosphorus-containing drugs.

3. Safety and environmental protection precautions

3.1. Safety:

-THPS is corrosive and irritating, and contact with the skin or eyes may cause burns.

-Wear protective equipment (such as gloves, goggles, etc.) during the operation.

-Store away from strong oxidants and alkaline substances.

3.2. Environmental protection:

-THPS is easily degraded in the environment,but phosphorus-containing wastewater may be produced during its production process, which needs to be treated.

-Wastewater can be treated by chemical precipitation method or biodegradation method to reduce the impact on the environment.

4. sum up

The production process of Tetrakis hydroxymethyl phosphonium sulfate（THPS)，CAS：55566-30-8 mainly includes hydroxymethylation, sulfation, purification and drying steps, with a wide range of applications, including fungicides, flame retardants and chemical intermediates. THPS has the advantages of high efficiency and environmental protection, but safety and environmental protection during the production and use. With the increase of industrial demand, the application prospect of THPS will be even broader.